A kidney transplant may be a treatment option for ESRD.
Kidney transplant is an alternative to dialysis in individuals who have severe renal disease. A kidney transplant is a surgical procedure that inserts a healthy kidney from a donor into your body. Your kidney(s) are left in place, unless they are causing problems like an infection or high blood pressure. The donor may be a living relative, a close friend whose tissue closely matches yours, or someone who has died and donated their organs. One transplanted kidney does the work of both failed kidneys.
In a kidney that fails, rejection of the transplanted kidney occurs within 3 to 4 months after the surgical procedure. The symptoms of rejection include: fever, weight gain, reduced urine output, and an increase in blood pressure. Blood tests will also show deteriorating renal function. Drugs that keep your immune system from rejecting the kidney can keep the transplanted kidney working. There have been major advances in the development of immunosuppressive agents, including the following:
Complications from kidney transplantation and using immunosuppressive drugs include:
Andrews PA. Renal transplantation BMJ. 2002;324(7336):530-534.
Chronic kidney disease (CKD) in adults. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115336/Chronic-kidney-disease-CKD-in-adults. Updated August 23, 2016. Accessed October 4, 2016.
Davis, CL, Delmonico, FL. Living-donor kidney transplantation: a review of the current practices for the live donor. J Am Soc Nephrol. 2005; 16(7):2098-2110.
What I need to know about kidney failure and how it's treated. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/health-information/health-topics/kidney-disease/kidney-failure-choosing-a-treatment-thats-right-for-you/Pages/ez.aspx. Updated September 15, 2010. Accessed July 2, 2013.
Last reviewed June 2016 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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