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Symptoms may not be present in early stages of MDS, but will appear as the disease progresses. If you experience any of these symptoms, do not assume it is due to MDS. Many of these symptoms can be caused by other conditions, like an iron deficiency or infection. It is still important to discuss these symptoms with your doctor. Early detection and treatment improve outcomes for both MDS and other health conditions.
Symptoms are mainly related to the low numbers of a particular blood cell. Each blood cell has a specific function in the body, so if they are not in a range that is considered normal, symptoms will appear.
The most common complication is anemia. It is because of a drop in the number of normal red blood cells, which decrease the body's ability to bring oxygen to body tissue. Symptoms of anemia may include:
In people with coronary artery disease, anemia may cause:
In people with a history of blood vessel problems in the brain, anemia may increase the risk of:
A drop in the number of normal white blood cells makes it harder for the body to fight infection. Symptoms may include:
A drop in the number of normal platelet cells makes it harder for blood to clot properly. Without clotting, even small injuries can lead to severe bleeding. Symptoms may include:
General information about myelodysplastic syndromes. National Cancer Institute website. Available at: https://www.cancer.gov/types/myeloproliferative/patient/myelodysplastic-treatment-pdq. Updated August 12, 2015. Accessed June 30, 2017.
Myelodysplastic syndrome. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114054/Myelodysplastic-syndrome-MDS. Updated January 13, 2017. Accessed June 30, 2017.
Myelodysplastic syndrome. Merck Manual Professional Version website Available at: http://www.merckmanuals.com/professional/hematology-and-oncology/leukemias/myelodysplastic-syndrome. Updated January 2017. Accessed June 30, 2017.
Signs and symptoms of myeloysplastic syndromes. American Cancer Society website. Available at: https://www.cancer.org/cancer/myelodysplastic-syndrome/detection-diagnosis-staging/signs-symptoms.html. Updated February 10, 2014. Accessed June 30, 2017.
Understanding myelodysplastic syndromes (MDS). MDS Foundation website. Available at: http://www.mds-foundation.org/what-is-mds. Accessed June 30, 2017.
Last reviewed June 2017 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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