A risk factor is something that increases your likelihood of getting a disease or condition.
It is possible to develop melanoma with or without the risk factors listed below. However, the more risk factors you have, the greater your likelihood of developing melanoma. If you have a number of risk factors, ask your doctor what you can do to reduce your risk.
Factors that may increase your chance of melanoma include:
Excessive Sun Exposure
Melanoma has been linked with exposure to ultraviolet (UV) radiation. Therefore, exposing your skin to UV rays from the sun or tanning lamps increases your odds of developing melanoma. People who live in sunny climates are exposed to more sunlight. People who live at high altitudes, where the sunlight is strongest, are exposed to more UV radiation. Blistering sunburns, even as a child, also increase the risk of developing melanoma.
People with certain occupations are also at higher risk due to their exposure to UV radiation. Some examples include construction workers, road crews, harbor masters, electrical fitters, and telephone wire repair employees.
Your Skin's Condition
Having melanoma once increases your risk of developing it again.
Having many moles or large moles increases your risk of melanoma. Also, irregular moles are more likely to turn into melanoma than normal moles. Irregular moles are characterized by:
Most melanomas are diagnosed in young adults and older adults.
Family members of people with melanoma are at greater risk of developing the disease than people with no family history of the disease. People with a disease called xeroderma pigmentosa (XP) are at a very increased risk of developing melanoma. This rare disease does not allow the body to repair sun-damaged DNA, therefore any sun exposure will result in damage and mutations that become melanomatous. It is not unusual for these people to develop hundreds of melanomas on their skin. Similarly, people with hereditary dysplastic nevus syndrome or familial atypical multiple mole melanoma (FAMMM) syndrome are also at increased risk for developing melanoma.
Caucasians are more likely than those of African , Hispanic, or Asian descent to develop melanoma.
Most people who develop melanoma tend to burn rather than tan when exposed to sunlight. These people tend to have fair skin, freckles, red or blonde hair, or blue eyes.
Melanoma. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115302/Melanoma. Updated August 26, 2016. Accessed October 6, 2016.
Melanoma skin cancer. American Cancer Society website. Available at: http://www.cancer.org/acs/groups/cid/documents/webcontent/003120-pdf.pdf. Updated January 17, 2013. Accessed April 8, 2013.
What is melanoma? Melanoma Research Foundation website. Available at: http://www.melanoma.org/understand-melanoma/what-is-melanoma. Accessed April 8, 2013.
5/18/2015 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T115302/Melanoma: Perez-Gomez B, Pollán M, Gustavsson P, Plato N, Aragones N, Lopez-Abente G. Cutaneous melanoma: hints from occupational risks by anatomic site in Swedish men. Occup Environ Med. 2004;61(2):117-126.
Last reviewed March 2016 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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