A risk factor is something that increases your likelihood of getting a disease or condition.
It is possible to develop GERD with or without the risk factors listed below. However, the more risk factors you have, the greater your likelihood of developing GERD. If you have a number of risk factors, ask your doctor what you can do to reduce your risk.
The most common risk factor is a poorly functioning lower esophageal sphincter (LES). The sphincter may be impaired or damaged by:
Gastroesophageal reflux disease (GERD). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated February 19, 2015. Accessed February 27, 2015.
Gastroesophageal reflux disease (GERD). Merck Manual Professional Version. Available at: http://www.merckmanuals.com/professional/gastrointestinal_disorders/esophageal_and_swallowing_disorders/gastroesophageal_reflux_disease_gerd.html. Updated May 2014. Accessed February 27, 2015.
Katz PO, Gerson LB, Velva MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108(3):302-328.
Mitre MC, Katzka DA. Pathophysiology of GERD: Lower esophageal sphincter defects. GERD in the 21st Century, Series 5. Practical Gastro website. Available at: http://www.practicalgastro.com/pdf/May04/MitreArticle.pdf. Published May 2004. Accessed February 27, 2015.
Symptoms and causes of gastroesophageal reflux (GER) and gastroesophageal reflux disease (GERD). National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ger-and-gerd-in-adults/Pages/symptoms-causes.aspx. Accessed February 27, 2015.
Understanding heartburn and reflux disease. American Gastroenterological Association website. Available at: http://www.gastro.org/patient-center/digestive-conditions/heartburn-gerd. Accessed February 27, 2015.
9/30/2008 DynaMed's Systematic Literature Surveillance: http://www.ebscohost.com/dynamed. Jacobson BC, Moy B, Colditz GA, Fuchs CS. Postmenopausal hormone use and symptoms of gastroesophageal reflux. Arch Intern Med. 2008;168(16):1798-1804.
4/25/2014 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Shimamoto T, Yamamichi N. No association of coffee consumption with gastric ulcer, duodenal ulcer, reflux esophagitis, and non-erosive reflux disease: A cross-sectional study of 8,013 healthy subjects in Japan. PLoS One. 2013;8(6):e65996.
Last reviewed June 2016 by Daus Mahnke, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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