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Bloqueadores de los Canales del Calcio

Canal de calcio - los bloqueadores son usados para tratar la hipertensión , angina , arritmias cardiacas y otras enfermedades cardiacas relacionadas.

Las medicinas en esta familia incluyen

  • amlodipina (Norvasc)
  • Clorohidrato de bepridil (Vascor)
  • diltiazem (Cardizem, Cardizem CD, Cardizem SR, Dilacor XR, Tiamate, Tiazac)
  • felodipino (Plendil)
  • isradipina (Dynacirc, Dynacirc CR)
  • hidrocloruro de nicardipina (Cardene, Cardene SR)
  • nifedipina (Procardia, Procardia XL, Adalat, Adalat CC)
  • nimodipina (Nimotop)
  • nisoldipina (Sular)
  • verapamil (Calan, Calan SR, Covera-HS, Isoptin, Isoptin SR, Verelan)
  • y otros
Calcio , Vitamina D

Posible Reducción de la Acción del Medicamento

Tomar suplementos de calcio y vitamina D podría interferir con algunos de los efectos de los bloqueadores del canal de calcio. 1 - 7

Ginkgo Biloba

Según un estudio en ratas, el extracto de ginkgo puede causar que el cuerpo metabolice nicardipina (un bloqueador del canal de calcio) más rápidamente, reduciendo de esa manera sus efectos. 8


1.   Bar-Or D and Gasiel Y. Calcium and calciferol antagonise effect of verapamil in atrial fibrillation. Br Med J (Clin Res Ed) 282: 1585 - 1586, 1981.

2.   Hariman RJ, Mangiardi LM, McAllister RG Jr, et al. Reversal of the cardiovascular effects of verapamil by calcium and sodium: differences between electrophysiologic and hemodynamic responses. Circulation 59: 797 - 804, 1979.

3.   Guadagnino V, Greengart A, Hollander G, et al. Treatment of severe left ventricular dysfunction with calcium chloride in patients receiving verapamil. J Clin Pharmacol 27: 407 - 409, 1987.

4.   Salerno DM, Anderson B, Sharkey PJ, et al. Intravenous verapamil for treatment of multifocal atrial tachycardia with and without calcium pretreatment. Ann Intern Med 107: 623 - 628, 1987.

5.   Luscher TF, Noll G, Sturmer T, et al. Calcium gluconate in severe verapamil intoxication. N Engl J Med 330: 718 - 720, 1994.

6.   Orr GM, Bodansky HJ, Dymond DS, et al. Fatal verapamil overdose. Lancet 2: 1218 - 1219, 1982.

7.   Kuhn M and Schriger DL. Low-dose calcium pretreatment to prevent verapamil-induced hypotension. Am Heart J 124: 231 - 232, 1992.

8.   Shinozuka K, Umegaki K, Kubota Y, et al. Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats. Life Sci. 2002;70:2783-2792.

Last reviewed agosto 2013 by EBSCO CAM Review Board

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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