Sjogren's syndrome is an inflammatory disease. The immune system destroys cells in exocrine glands. It occurs most often in the tear and salivary glands. It is a lifelong condition. There are two types:
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The causes of Sjogren's are unknown. Contributing factors may include:
Factors that increase your risk for Sjogren's include:
Symptoms may include:
In some cases, other parts of the body are affected as well. These include:
The doctor will ask about your symptoms and medical history. A physical exam will be done. You may be referred to a specialist.
Your bodily fluids and tissues may be tested. This can be done with:
Your eyes may be tested. This can be done with:
Images may also be taken of your bodily structures. This can be done with a chest x-ray .
There is no cure for Sjogren's. No treatment can restore the ability of the glands to produce moisture. The goal of treatment is to relieve symptoms.
To help relieve dryness:
To relieve joint and muscle pain:
To relieve inflammation / swelling:
This condition is generally benign. However, people with severe cases are at increased risk for developing non-Hodgkin’s lymphoma . This is a cancer of the white blood cells. Your doctor will need to monitor you for this.
American Autoimmune Related Diseases Association, Inc.
Sjogren's Syndrome Foundation
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Kassan SS, Montsopolous HM. Clinical manifestations of Sjogren’s disease. Arch Intern Med. 2004;164:1275-1284.
Papas, et al. Successful treatment of dry mouth and dry eye symptoms in Sjogren's syndrome patients with oral pilocarpine: a randomized, placebo-controlled, dose-adjustment study. J Clin Rheumatol. 2004;10:169-177.
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Sjogren's syndrome. American College of Rheumatology website. Available at: http://www.rheumatology.org/Practice/Clinical/Patients/Diseases_And_Conditions/Sj%C3%B6gren_s_Syndrome/ . Updated July 2012. Accessed August 15, 2013.
Venables PJ. Management of patients presenting with Sjogren's syndrome. Best Pract Res Clin Rheumatol. 2006;20:791-807.
What you need to know about Sjogren's syndrome. Cleveland Clinic website. Available at: http://www.clevelandclinic.org/health/health-info/docs/0200/0220.asp . Accessed August 15, 2013.
Last reviewed August 2013 by Rosalyn Carson-DeWitt, MD; Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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